1974-1979

The band held their rehearsals at Performance Studios on East 20th Street in NYC built and co-managed by Thomas Erdelyi and Monte A. Melnick. Impressed by the group, Erdelyi became the band's unofficial manager, and Melnick their tour manager. Soon after the band was formed, Dee Dee realized that he couldn't sing and play bass at the same time, so Joey became the band's lead vocalist (Dee would continue, however, to count off each song's tempo with his trademark rapid-fire shout of "1-2-3-4!"). Joey would also realize that he could not sing and play drums at the same time, and left the position of drummer. While auditioning new drummers, manager Thomas Erdelyi would often take the drums and demonstrate to auditioners how to play the songs. It became apparent that he was able to play the group's songs better than anyone else, and he joined the band as drummer Tommy Ramone.

The band played their first concert on March 30, 1974 at Performance Studios in New York. The songs they played were very fast and very short; most clocked in at under two minutes. In the early 1970s, a new music scene emerged in New York when many bands started to play in clubs on the Lower East Side of Manhattan, such as Max's Kansas City, and most famously CBGB's. Ramones concerts at CBGB's became legendary, due in part to their brevity: most concerts were twenty to thirty minutes long, much shorter than their contemporaries', and are often described by their witnesses as extremely fast, crude, energetic and desperate. The Ramones' live set was so short they sometimes needed to repeat it twice a show. Mostly, the songs would be performed back to back, but were also regularly interrupted by arguments among the band members. A few super–8 movies of these shows have survived, and are present in a couple of the band's later videos.

After garnering considerable attention for their performances at CBGB's, the group was signed to a recording contract by Seymour Stein of Sire Records in Autumn 1975. They soon recorded their debut album, Ramones on an extremely low budget; about $6,400. The band was plagued by hostile audience reactions outside of New York City; it wasn’t until they made a small tour of England that they began to see the fruits of their labor: a performance at The Roundhouse in London on July 4, 1976 (second-billed to the Flamin' Groovies) was a huge success. Their appearance galvanized the burgeoning UK punk rock scene, inspiring future punk stars, including members of The Clash, The Damned, and the Sex Pistols. The Flamin' Groovie/Ramones double-bill was successfully reprised at The Roxy in Los Angeles the following month, which also inspired local Los Angeles musicians.

On December 31, 1977, the Ramones recorded It's Alive, a double live concert album, at the Rainbow Theatre, London, which was released in April 1979. The title is a reference to the 1974 horror movie of the same name. Upon returning from England, they found themselves prophets without honor in their own country: their subsequent two albums, Leave Home and Rocket to Russia (both 1977), failed to become the hits the band desired. Both records were co-produced by Tony Bongiovi, the cousin of Jon Bon Jovi. Tommy, tired of touring, left the band at this time but continued to produce; he was replaced by Marc Bell, who became Marky Ramone.

The first three Ramones albums mainly contained songs written during their pre-contract years. Their fourth album, Road to Ruin, was fully packed with brand new songs, including some stylistic flourishes — acoustic guitar, several ballads, songs over three minutes — that might have been concessions to mainstream tastes, but the album still failed to chart highly. Despite excellent reviews for both their albums ("Rocket to Russia is the best American rock & roll of the year and possibly the funniest rock album ever made," Dave Marsh wrote in Rolling Stone magazine) and their live performances, the Ramones remained a cult band. The highly publicized dissolution of the Sex Pistols in 1978 seemed to signal the end of punk as a viable commercial force and branded the Ramones as forever outsiders.